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Reviews of "SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade"

Reviewers: Chiranjib Chakraborty | 📗📗📗📗◻️ • Peter A Ward (University of Michigan) | 📗📗📗📗◻️

Published onFeb 14, 2022
Reviews of "SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade"

To read the original manuscript, click the link above.

Summary of Reviews: This preprint explores binding of SARS-CoV-2 spike protein with lipopolysaccharide (LPS), and its role in increased inflammatory response. Reviewers find presented evidence reliable, while exercising caution with presented generalizations regarding use of drugs blocking TLR4-LPS binding as potential COVID treatment.

Reviewer 1 (Chiranjib Chakraborty) | 📗📗📗📗◻️

Reviewer 2 (Peter A Ward) | 📗📗📗📗◻️

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below. 


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