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Reviews of "A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa"

Reviewers: M Hossain (University of Dhaka) | 📘📘📘📘📘 • Adriana Heguy (NYU Langone Medical Center) | 📘📘📘📘📘

Published onAug 30, 2021
Reviews of "A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa"
key-enterThis Pub is a Review of
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
Description

AbstractThe progression of the SARS-CoV-2 pandemic in Africa has so far been heterogeneous and the full impact is not yet well understood. Here, we describe the genomic epidemiology using a dataset of 8746 genomes from 33 African countries and two overseas territories. We show that the epidemics in most countries were initiated by importations, predominantly from Europe, which diminished following the early introduction of international travel restrictions. As the pandemic progressed, ongoing transmission in many countries and increasing mobility led to the emergence and spread within the continent of many variants of concern and interest, such as B.1.351, B.1.525, A.23.1 and C.1.1. Although distorted by low sampling numbers and blind-spots, the findings highlight that Africa must not be left behind in the global pandemic response, otherwise it could become a breeding ground for new variants.

To read the original manuscript, click the link above.

Summary of Reviews: This preprint explores the genetic changes of SARS-CoV-2 in Africa by offering an in-depth epidemiological analysis of virus introduction, circulation, and evolution over a year. Reviewers agree that the claims are reliable and supported by the data.

Reviewer 1 (M Hossain) | 📘📘📘📘📘

Reviewer 2 (Adriana Heguy) | 📘📘📘📘📘

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below. 


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