Review 1: "Sofosbuvir protects human brain organoids against SARS-CoV-2"
This study claims brain organoids are permissive to SARS-CoV-2 infection and use this model to demonstrate neuroprotective effects of Sofosbuvir. While the findings are compelling, the experiments performed and the data offered are insufficient to deem the stated claims reliable.
Created on
Sep 16, 2020
Published on
Sep 16, 2020
Cite As
Maoz, B. (2020). Review 1: “Sofosbuvir protects human brain organoids against SARS-CoV-2.” Rapid Reviews Infectious Diseases. https://doi.org/10.1162/2e3983f5.93696242
DOI
10.1162/2e3983f5.93696242
Contributors
BM
Ben Maoz
Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel ; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel